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By integrating patient-reported outcomes with mechanistic biomarkers, future trials can bridge the translational gap while maintaining ethical and scientific rigor

[1] [2] A polypeptide is a longer, continuous, unbranched peptide chain

Instead, FIN56 treatment resulted in loss of GPX4 protein through post-translational degradation, and blocked mevalonate-derived production of lipophilic antioxidants, such as coenzyme Q 10 (Figure 1)

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