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doi: 10.7759/cureus.28218

Double-Blind, Half-Face Study Comparing Topical Vitamin C and Vehicle for Rejuvenation of Photodamage

Before entering the circulatory system most of the quercetin ingested from the intestinal cavity is converted into conjugated metabolites ( via the epithelium, where it is metabolized and converted into a bioavailable form ( via the intestines, but small amounts are excreted by the kidneys in the urine ( Quercetin reportedly exerts powerful anti-inflammatory effects, mainly via inhibition of cytokine production, reduction of cyclooxygenase and lipoxygenase expression, and maintaining the stability of mast cells ( Streptococcus suis -induced inflammation by inhibiting the activation of p38 mitogen-activated protein kinase, extracellular signal-related kinases (ERK1/2), and nuclear factor kappa B (NF-B)
Its crucial to approach peptide therapy under the guidance of qualified healthcare professionals to ensure safe administration and monitor potential side effects
