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As eIF2 phosphorylation and ATF4 expression were induced by erastin or cystine starvation independent of PERK phosphorylation, we examined whether another eIF2-ATF4 upstream activator, GCN2 12 , was activated in this context
10.1016/S0306-4522(00)00294-3 138 PizzutoR.PaventiG.PorcileC.SarnataroD.DanieleA.PassarellaS
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Several studies used LPS both experimentally and clinically to trigger systemic and hepatic inflammation
