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Description
In this multicenter study, data of 1327 subjects were obtained, and the analysis showed a reduction in the Visual Analog Scale (VAS) score for pain by the 4th week in 74% of subjects, with 82% of subjects reporting good to excellent tolerability

The preclinical evidence supports cautious optimism

They reflect a cascade of regenerative processes that compound over the 12 to 20 week protocol window
The B12-intrinsic factor complex travels to the terminal ileum, where it binds to specific receptors (cubilin-amnionless complex) and is absorbed through receptor-mediated endocytosis
