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Despite the classification of EoPE and LoPE attributing the cause to the placenta and maternal, respectively, it is important to clarify that the combination of both maternal and placental factors can contribute to the development of both types of preeclampsia

10.1016/s0009-9120(99)00022-3 [DOI] [PubMed] [Google Scholar] Sever A

Without biologically based markers for reliable diagnosis, ASD diagnosis can be subject to bias and can fail to identify children with ASD early enough during the critical period of development, thus predisposing them to suboptimal developmental outcomes [166]

It's also about how long your protocol needs to run before results become visible