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The pathogenesis of DPN is intricate and remains not completely understood

(2021) 11:a038414

Since these cells would be expected to reduce the incoming DHA to ascorbate, there remains the problem of how that ascorbate would exit the cells into the brain interstitium

Understanding the metabolic signatures associated with different microglial activation states could lead to the development of novel therapeutics that specifically target these metabolic pathways (Blanger et al., 2011
