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Creatine supplementation is widely recognized for its role in enhancing muscle strength, power, and lean mass

Then, -ketoglutarate can enter back into the TCA for completing the cycle

Availability of data and materials Data described in the manuscript will be available upon request and approval by the UK Biobank ( Declarations Ethics approval and consent to participate This research has been conducted using the UK Biobank Resource under application number 42468 and other large studies and consortia providing publicly available summary statistics