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Epilepsia 37:258261

In APP/PS1 transgenic mice, the standard animal model for Alzheimer disease pathology, Dihexa restored spatial learning to levels indistinguishable from healthy controls

In the study, 20 long-distance master runners were asked to participate in an eight-week training program

While GSH has long been recognized as a key brain antioxidant, its role in neurodegenerative diseases is now being unraveled with mechanistic clarity: future research will likely focus on activating astrocytic Nrf2 signaling to enhance glutamate cysteine ligase (GCL)-mediated GSH synthesis, exploring the role of MCT1/2 transporters in neuronal GSH precursor supply, and dissecting how oxidative stress modulates microglial activation via pathways like NF-B-dependent proinflammatory cytokine secretion (Sun et al., 2022)