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Description
A new primaquine analogue, tafenoquine (WR 238605), for prophylaxis against Plasmodium falciparum malaria
& Kreider, R

Oinuma I, Katoh H, Harada A, Negishi M

Given that the biosynthesis of these octadecanoids is COX-independent, this finding may explain why COX-inhibitors (e.g., ibuprofen) only show weak antinociceptive effects in UVB-induced mechanical allodynia in rodents
