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Description
Therefore, targeting IGFs may help solve the problem of tumor drug resistance

Retatrutide is an investigational peptide compound that acts as a triple agonist, targeting three hormone receptors simultaneously: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

JHC, how is that possible
For instance, Fer-1, similar to other hydrophobic drug candidates, is unsuitable for clinical development because of its limited capacity to traverse the blood-brain barrier (BBB) and its poor water solubility [216]
