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Regardless of barrier penetration, in vivo exposure to microplastics plays a significant role in dopamine neuron degeneration, representing a non-independent risk factor that cannot be overlooked in PD pathogenesis (34).Both in vivo and in vitro experiments demonstrated that Western blotting and immunofluorescence revealed PS-NPs induced pyroptosis, disrupted autophagic flux, and reduced the levels of proteins involved in autophagosome-lysosome fusion

Am J Respir Crit Care Med 2000;162:566570

Multiple molecular and cellular mechanisms of the antitumour effect of dihydromyricetin (review)

& Yudkoff, M