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First, AA is mediated by COX-1 or COX-2 to form prostaglandin G2 (PGG 2 ), and then, the same enzyme catalyzes the formation of prostaglandin H2 (PGH 2 )

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High levels of acetaldehyde can cause amnesia, which is why someone can wake up the day after a night of heavy drinking and wonder, "What happened last night." When ethanol intake is high, alcohol dehydrogenase activity is insufficient to process the amount of acetaldehyde that accumulates, which can lead to acetaldehyde buildup in the liver

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