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Author contributions I-YC, PL, and DS designed the research
Fibrotic extracellular matrix activates a profibrotic positive feedback loop
Peripherally, PNIs result in the immediate loss of both motor and sensory function distal to the injury, Wallerian degeneration of the distal nerve segment, neuromuscular junction denervation and degradation, and muscle atrophy (Brushart, 2011)
There are many internal and external ways our DNA gets damaged
