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Additionally, during AP, acinar cells regulate the MARCH3/NLRP3 axis via high expression of miR-24-3p, which promotes M1 polarization and pyroptosis of peritoneal macrophages, contributing to abdominal inflammation

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Following 14 days of treatment, TLC-2716 caused dose-dependent improvements in atherogenic plasma lipids (exploratory outcomes), including TG, RC, TC, non-HDL-C, LDL-C and the number of LDL and small LDL particles (Fig

Biomechanical and Functional Tests As described previously [13], biomechanical and functional tests were performed