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Description
A change occurring within minutes to hours is more consistent with early signaling modulation than with slower transcriptional remodeling alone
At a determined period of time (e.g., 6 hours, 12 hours, 1 day, 2 days, 3 days, 4 days, 5 days, 6 days, 7 days, and 14 days for testing the pharmacokinetics of a formulation or composition over a 1 or 2 week period), the test animal is euthanized and the inner ear removed and tested for the presence of the otic agent
doi: 10.18632/aging.v12i20 148 QiuZWangXYangZLiaoSDongWSunTet al
Just treating one aspect often isn't enough
