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Recently, single-cell transcriptomics revealed that P53 pathway activation-induced specific depletion of matrix TAC, but not HFSCs, is associated with early-stage human hair graying 20

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Notably, sodium butyrate supplementation has been linked to decreased levels of inflammatory markers such as interleukin-1 (IL-1), IL-6, and tumor necrosis factor- (TNF-), leading to improved immune responses and reduced stress during critical growth phases [16,17]

Phytochrome-interacting transcription factors PIF4 and PIF5 induce leaf senescence in Arabidopsis