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Under stress, mitochondria release proinflammatory mediators, such as ATP, cardiolipin, ROS, and mtDNA, which, when released into the cytoplasm or extracellular space, can promote inflammation and trigger senescence or senescence-associated chronic diseases [208]

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After 6 months on the low carbohydrates diet, serum levels of neurofilament light chain, a biomarker of neuroaxonal damage, were significantly reduced compared with regular diet in patients with relapsing-remitting MS (171)

PMC7726887