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Description
In contrast, PPMS is defined by a gradual and continuous worsening of neurological function from disease onset, without distinct relapses or remissions

& Gaunitz, F

E., Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared With DAmphetamine in Healthy Subjects, Frontiers in Pharmacology 8 (2017): 617

Sachdev S, Bruhn L, Sieber H, Pichler A, Melchior F, Grosschedl R
