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2.2 Synovium and infrapatellar fat pad In OA, the synovial membrane exhibits marked pathological remodeling characterized by lining layer hyperplasia, sublining fibrosis, increased vascularization, and infiltration of immune cells, particularly macrophages, lymphocytes, and mast cells
This seems to be the most sensitive indicator of a delicate imbalance with glutathione and other factors needed to recycle vitamin C
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