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Description
This dose-tolerability relationship provides useful guidance for clinical protocol development
Supplied as lyophilised powder, third-party tested
Sibutramine, a popular antiobesity drug used worldwide since 1997, was withdrawn from the European and US markets in 2010 because of safety concerns [27,28]
While the clinical trials demonstrated excellent safety in generally healthy obese adults, individual medical histories may reveal concerns not apparent in trial populations
