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Suicidal ideation among transgender and gender diverse adults: a longitudinal study of risk and protective factors

[56] Serum haptocorrin binds 80-90% of circulating B 12 , rendering it unavailable for cellular delivery by transcobalamin II

Of course we cant know if this imposed reduced frequency had any impact however the word pernicious springs to mind

Neelakantan H, Vance V, Wetzel MD, Wang HY, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high-fat diet-induced obesity in mice. Biochem Pharmacol. 2018 Jul;154:161-171. doi: 10.1016/j.bcp.2018.05.003. Epub 2018 May 5. PMID: 29738706; PMCID: PMC6015571
