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Both cysteines are conserved in most chloroplastic orthologs from terrestrial plants whereas only Cys119 is present in the cytosolic AtAPK3 or in algal representatives (Figure 2 and Supplementary Table 3)

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Thus, vCD44BP alters the distribution of CD44 in infected FRCs, preventing its redistribution after infection

Derivatives like LA67, triptolide-succinic acid ester, and compound 33 demonstrate increased bioavailability, targeted cytotoxicity, and innovative therapeutic options, including photodynamic therapy and NO-releasing capabilities, thus broadening triptolide's clinical application potential in cancer treatment [1017, 1018]
