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The nuclear receptor Nur77, which is essential for melanoma cells to adapt to the metabolic stress of glucose starvation, promotes FAO by protecting TP from oxidative inactivation, thereby maintaining ROS levels in cells to facilitate cell survival [142]

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Interestingly, wah-1(bon89) mutants showed a stronger upregulation of [gst-4p::GFP::NLS] compared to controls when grown on OP50 rather than HT115 (Fig