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Regarding the effects on miR-21, curcumin treatment was found to reduce miR-21 promoter activity and expression in a dose-dependent manner by inhibiting AP-1 binding to the promoter and inducing the expression of the tumor suppressor Pdcd4

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Maier JA, Castiglioni S, Locatelli L, Zocchi M, Mazur A (2021) Magnesium and inflammation: advances and perspectives

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