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Description
Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor

In murine primary hepatocytes, knockdown of Grb14 leads to a significant decrease in insulininduced processing and expression of sterol regulatory elementbinding protein 1c, highlighting its role in lipid metabolism [26]

The denaturants then must be completely removed to allow proper refolding of the protein
4-Hydroxy-2-nonenal, a Lipid Peroxidation Product, as a Biomarker in Diabetes and its Complications: Challenges and Opportunities