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however, previous studies done on liver fibrosis and cardiac fibrosis in vivo and in vitro demonstrated that VCN was able to reduce the accumulation of fibrotic components possibly through its main pharmacological mechanism by targeting the PDE1A, where the latter has been identified as a key regulator of fibroblast activation and ECM remodeling in the heart 87
Tissue distribution studies reveal that mercury primarily accumulates in the liver, kidneys, and brain
Here, we briefly overview glutathione function and its metabolism, with a particular focus on GGT
Curr Neurovasc Res 2:375386
