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The mean fluorescence intensity of CellROX was significantly higher in immune cells from TLS than those from the spleen or peripheral blood (Supplemental Figure 4)
In the liver, the MRP transporters are mainly present on the epithelial cells of the bile duct, on the sinusoidal membrane, and on the basolateral membrane [109]
More recently there has been cautious optimism among groups who believe that some studies were perhaps stopped prematurely and that while monotherapies might not be the way forward, combination therapies may hold greater promise [54,57,58,59]
