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Cholesterol modulates ferroptosis susceptibility by altering metabolic flux in the mevalonate pathway through targeted degradation of squalene epoxidase (SQLE), the rate-limiting enzyme in cholesterol biosynthesis

Vitamin B12 (Methylcobalamin or Cyanocobalamin): Essential for red blood cell production, neurological health, and energy metabolism

In addition to the aforementioned role through which A1AT acts with antioxidant action by increasing endogenous antioxidant enzymes, such as superoxide dismutase and catalase, it also exerts indirect mechanisms of protection against oxidative stress

Research shows that men suffer from the disease up to four times more often than women, but with age this ratio decreases and after the age of 60