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Basaran, N

Notably, ED may persist or even worsen despite appropriate antihypertensive treatment, as certain medications, especially thiazide diuretics, beta-adrenergic blockers, and aldosterone antagonists, have been linked to detrimental effects [45]

Also, its common that when a drug interaction website lists something as mild, its referring to an interaction thats purely theoretical and may or may not play out in reality

Future research must prioritize dynamic regulation within this networkhow feedback loops adapt to stressors such as inflammation or metabolic imbalance, and how disruptions cascade across organs