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Since 90% of the bodys serotonin originates in the gut, modulating enteric serotonin production could influence central serotonergic tone through vagal afferents that relay gut signals to brain serotonin-producing raphe nuclei

Hyperhomocysteinemia: An Independent Risk Factor for Thrombosis Recent studies underline the major role of moderate hyperhomocysteinemia on the odds of developing both arterial and venous thromboembolisms (Boers, 1997a