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It is unknown whether tirzepatide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide -induced rodent thyroid C-cell tumors has not been determined

doi: 10.1017/S0029665100000094 141

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This process is highly efficient in rodent models, in which complete remyelination occurs within weeks or months following the experimental insult