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This novel method produced medicines that are capable of sustaining therapeutic drug levels for a minimum of 24 h, facilitating once-weekly administration for the majority of these drugs (Holst 2019)

Diabetes Obes Metab 13(11):9901000

Vitamin D deserves separate mention because fat loss releases stored vitamin D from adipose tissue, temporarily increasing blood levels, but long-term reduced fat intake can lead to deficiency
