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tirzepatide vs semaglutide weight loss efficacy Tirzepatide (Zepbound; Eli Lilly and
Description
These cardiovascular benefits have influenced treatment algorithms, with guidelines recommending GLP-1 receptor agonists with proven cardiovascular benefit for patients with type 2 diabetes and atherosclerotic cardiovascular disease
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NICE technology appraisal TA875 (2023) recommends Wegovy within a specialist weight management service for adults with a BMI of 35 kg/m or above (or 30 kg/m in certain high-risk groups) and at least one weight-related health condition, for a maximum of two years

Both compounds are used in comparative metabolic research
