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The complaints also allege that the touted studies are on individual ingredients and do not actually measure the extracts together in a single supplement, so that while they claim to have clinical support for the components of Lemme GLP-1 Daily, they did not study the combination of those extracts in a single supplementmeaning that the supplement has not been clinically tested. Many courts, including those in New York and California, preclude private individuals from challenging advertising based on the advertiser lacking adequate substantiation for their claims, as the plaintiffs have done in the Lemme complaints

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The amino acid serves double duty in compounded formulations, functioning both as a pharmaceutical stabilizer that protects the peptide structure and as a bioactive compound that addresses one of the biggest concerns with GLP-1 therapy: the loss of lean muscle mass