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Description
Especficamente, la cardioproteccin inducida tras la activacin de la va RISK est mediada por la inhibicin de la apertura del PTPM, el bloqueo de la sobrecarga de calcio y la activacin de varios mecanismos antiapoptticos7
Chen, H., Sullivan, G
It demonstrates that the GLP-1 receptor's activation pathway is "convergent" rather than "pathway-specific": multiple distinct binding events at the extracellular surface can trigger the same conformational rearrangement at the intracellular surface
Its half-life varies based on dosage and patient metabolism
