glp-1 liver enzymes receptor agonists may protect the during alcohol consumption New daily GLP-1 pill reduces

This work demonstrated that GLP-1RA treatment was associated with a significant 29% reduction in MALOs compared to non-use (IRR: 0.71, 95%CI: 0.57-0.88, P = 0.003) over a median follow-up of approximately 70,045 patient-years

Additional studies demonstrated that SREBP-1c -/- mice had impaired induction of hepatic genes coding for fatty acid biosynthesis (e.g., acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase) compared to wild type mice [17]

For people with MS who also have obesity or type 2 diabetes, GLP-1 medications may be worth discussing with a neurologist and primary care provider, though their long-term impact on MS is still unknown

Gallbladder Disease: Including gallstones or the need for emergency gallbladder removal (cholecystectomy)