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[23] [26] Current evidence is insufficient to establish efficacy, optimal dosing, or safety profiles in RA populations without diabetes or obesity

Individuals with BED frequently experience comorbid conditions including obesity, type 2 diabetes, hypertension, and metabolic syndrome

Purifying long peptides is difficult, plus these GLP-1 peptide drugs have been modified to include a fatty acid side chain, and lipids themselves can be very difficult to purify, because theyre very hydrophobic, and tend to stick to the [purification] column, says Levine

Boylan MO, Glazebrook PA, Tatalovic M, Wolfe MM
