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A case can be made for a test and treat approach at the time of first (aspirin) prescription, when there is probably an increased risk of peptic ulceration and gastrointestinal bleeding. The low rate of bleeding episodes in the trial, possibly partly linked to patients using protective treatments, and the evidence that protection against bleeding might be transient meant there was not a strong case to extend H

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Treatment [10] [14] [15] Hemodynamically unstable patients: : emergency exploratory laparoscopy/laparotomy to obtain hemostasis Suturing or cauterization of the ruptured section or cystectomy Consider oophorectomy in intractable hemorrhage Hemodynamically stable patients: conservative management with analgesics and observation Consider outpatient monitoring with close follow-up for patients with: Minimal hemoperitoneum Stable Hb on serial monitoring over 46-hours [16] Inpatient management if there is evidence of significant and/or ongoing hemorrhage [10] Monitor vital signs, hemoglobin, and hemoperitoneum size on ultrasound
