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While peptide-based GLP-1 receptor agonists such as Exenatide, Liraglutide, Dulaglutide, and Semaglutide have demonstrated strong efficacy, there remains significant interest in developing next-generation therapies

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Mojsov S

Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine

The origins of GLP-1 drugs trace back to a fascinating source a compound found in the saliva of the Gila monster, a venomous lizard native to the American Southwest
