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The search strategy combined Medical Subject Headings (MeSH) and free-text terms related to GLP-1 receptor agonists, pregnancy, preconception, obesity, polycystic ovary syndrome, and reproductive safety, with Boolean operators (AND, OR) to maximize retrieval

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Yet, there was no significant change in first-phase insulin secretion or insulin sensitivity by clamp studies (122)

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L., Fields, J

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Approach 2: Start at a mid-range dose

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