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Key secondary objectives were to compare the effects of semaglutide 2.4mg to placebo regarding mortality, heart failure, cardiovascular risk factors, including glucose metabolism, body weight and kidney function

[16] The medication's phase 3 clinical trial program demonstrated reductions in hemoglobin A1c of approximately 1% with the 0.75 mg and 1.5 mg doses of the medication, along with approximately 5 pounds of weight loss on average

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This makes retatrutide a more comprehensive treatment for weight loss and metabolic health