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Typical GLP tolerance and side effect profile These efficacy results approach those seen with weekly injectable formulations , even though oral delivery historically posed challenges due to absorption limitations in the gut

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Some formulations can be kept at room temperature for limited periods, but exceeding these limits compromises potency

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The two medications work through completely separate mechanisms

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However, drugs in this class can increase the risk of heart failure in some people, and may also cause fluid retention in the legs and feet

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