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Non-responders or those with severe nausea may require dose reduction or medication switch

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Moreover, menopause can affect overall health and increase heart disease and weight gain risk

What the Human Evidence Actually Shows (in Populations That Are Not PCOS) Because the PCOS-specific evidence is empty, the fairest way to gauge retatrutides insulin-sensitizing potential is to examine, accurately, what it did in the populations where it was studied and to keep firmly in mind that none of these populations were selected for PCOS