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In a pre- and postnatal development study in pregnant cynomolgus monkeys, subcutaneous doses of 0.015, 0.075 and 0.15 mg/kg twice weekly (1.3-, 6.4- and 14-fold the MRHD) were administered from Gestation Day 16 to 140

3 Results 3.1 Molecular dynamics (MD) simulation of GLP-1 complexed to loop remodeled GLP-1R The initial structure of GLP-1R was retrieved from the reported active structural complex of GLP-1R with the native GLP-1 (PDB: 5VAI)

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To maintain that firmness long-term, periodic maintenance treatments are often recommended
