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However, GLP-1 therapies have historically carried substantial costs

Adv Ther 2022;39(4):17721783
Retatrutide activates three hormone receptors: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors

Physiology of the DPP4 enzyme in glucose metabolism Dipeptidyl peptidase-4 (DPP4) is a multifunctional enzyme expressed on the surface of a variety of cell types, including immune, epithelial, and endothelial cells