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To mitigate this, initial dosing of exenatide usually starts low (5 g BID) then increases to 10 g BID after a month
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When the clinical suspicion for cardiac amyloidosis is high, a semiquantitative grade 2 (myocardial uptake bone) on 99mTc-PYP Scan combined with negative free light chain and immunofixation assays (to rule out AL cardiac amyloidosis) can diagnose ATTR cardiac amyloidosis and exclude AL cardiac amyloidosis w/ 100% PPV
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