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GIP (142) Asp 21 may form a hydrogen bond with GIPR Arg 131 and the mutation of GIPR Arg 131 to Ala decreases the affinity and activity
That is one reason more patients are asking about GLP-1 injections for weight loss
doi:10.1210/er.2015-1084 9
To gain approval, one has to develop good documentation, he explains
