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These agents include thiazolidinediones (PPAR- agonists), dipeptidyl peptidase-4 (DPP-4) inhibitors, sulfonylureas, sodium-glucose co-transporter 2 (SGLT2) inhibitors, -glucosidase inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists

But definitive answers may only come with even longer follow-ups and more widespread usage

Originally developed for managing type 2 diabetes, these medications are now making headlines for their broader impact on weight, metabolic health and cardiovascular health

7,50,51 As researchers dive deeper into their multifaceted properties, these medications exhibit the potential to offer therapeutic benefits across a spectrum of diseases in human populations