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Semaglutide works systemically through multiple mechanisms: it enhances insulin secretion in response to elevated blood glucose, suppresses glucagon release, slows gastric emptying, and acts on appetite centres in the brain to increase satiety and reduce hunger

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The partnership with Eurofarma, which began last year, has allowed local versions of the Danish pens to reach previously underserved regions at more competitive prices, in a strategy designed to protect its market share

this mechanism of action has potential implications when considering pre-procedure fasting times and the choice of anesthesia technique