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While the exact mechanisms remain unclear, several factors are implicated, including nutritional aspects, mechanical unloading, loss of lean mass, and alterations in the secretion of gut hormones and adipokines [8, 10]

For example, some genetic profiles suggest better metabolic flexibility during fasting, while others indicate a need for more frequent eating windows to maintain stable blood sugar and prevent nutrient depletion

Gastroparesis can cause more serious complications

JAMA Netw Open 4(1):e2033457 [DOI] [PMC free article] [PubMed] [Google Scholar] 65.Kanbay M, Siriopol D, Copur S, Hasbal NB, Guldan M, Kalantar-Zadeh K et al (2024) Effect of bimagrumab on body composition: a systematic review and meta-analysis